Platelet-targeted fibrinolysis enhances clot lysis and inhibits platelet aggregation.
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چکیده
منابع مشابه
Platelet-targeted fibrinolysis enhances clot lysis and inhibits platelet aggregation.
BACKGROUND Although plasminogen activator therapy has been shown to reduce mortality in patients with severe myocardial infarction, several problems fuel the search for more potent and specific thrombolytic agents. METHODS AND RESULTS To explore the effect of plasminogen activator targeting to platelets, we covalently linked urokinase that had been modified with N-succinimidyl-3-(2-pyridyldit...
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ژورنال
عنوان ژورنال: Circulation
سال: 1991
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.84.2.805